ABSTRACT
Background: Non-communicable diseases like DM2, cardiac diseases, chronic respiratory disorders, brain disorders like stroke have created a havoc in developing countries, especially India which harbors 2nd largest population in the world. The present study was planned in this area to capture the data regarding epidemiology, risk factors of DM2, and use this information to plan health program to formulate effective preventive measures, including raising general awareness about the disease in that geographical area.Methods: The present cross sectional study was carried out in population of Karad area of Satara district in Maharashtra state. The study duration was of 1 year, from 1st February 2018 to 1st February 2019.Results: Out of total 1100 study population in the present study, 99 (9%) were diagnosed as diabetics (DM2) while 1001 were normal/non-diabetics. Majority of the diabetic patients were of the age group 41 to 50 years. Females (47%) showed slightly more prevalence of diabetes as compared to males (53%). Majority of the diabetic patients were having sedentary lifestyle, which consisted of 69 patients (70%), which was statistically significant, as compared to non-diabetic group.Conclusion: Thus, findings of the present study amply clarifies that DM2 is on longer a disease of urban population. Its prevalence is increasing in rural population, as well. Lack of awareness, sedentary lifestyle, faulty dietary habits, etc. are some of the reasons for such high prevalence.
ABSTRACT
Background: Derangements in stress hormone levels i.e. steroids, thyroid hormones is routinely encountered in almost all the seriously ill patients, which have been found to be associated with morbidity and mortality. The present study was planned to assess the thyroid hormone derangements in seriously ill patients, with respect to mortality.Methods: The present study was a retrospective, observational, record-based study done at Krishna Institute of Medical Sciences, Karad, Maharashtra, India.Results: Out of total 170 patients, 108 were females (63.5%) and 62 (36.4%) were males. On age wise analysis, it was found that majority of the patients were in the age group >50 years comprising of 78 (45.8%) patients. Thyroid hormonal status was deranged in 94 patients (55%), out of which 53 (31%) died and 41 patients (24%) were alive. Most common derangement was seen in free T3 (triiodothyronine), with 60% of the patients showing lowered values, 35% showing raised values and 5% showing normal values. T4 (thyroxine) levels were normal in major bulk of the patients.Conclusions: Serum T3 levels should be routinely done in critically ill patients, to detect any thyroid disorders, which might go undetected until it is too late.
ABSTRACT
Background: Subclinical hypothyroidism (SCH) is defined by increase in serum thyroid stimulating hormone (TSH) and free thyroxine (FT4) and free triiodothyronine (FT3) levels within normal range, coupled with absence of typical clinical symptoms. The present study was undertaken to analyse the SCH associated comorbidities, especially lipid disturbances, thyroid autoantibodies, etc.Methods: The present study was retrospective observational study, which was carried out at a tertiary health care center.Results: Out of the 100 patients, majority were in the age group 21 to 30 years (31 patients), followed by 26 patients in age group >51 years and least in age group 41 to 50 years. Prevalence showed female predilection, with female: male ratio of 1.9:1. Most common symptom reported was general fatigue, which was encountered in 40 patients, followed by weight gain, menstrual abnormalities, and constipation. 10 patients were asymptomatic. Serum TSH range in the patients was 5 to 21.1 µIU/l, while mean TSH was 10.9 µIU/l. 20 patients were found to have serum TSH>10.Conclusions: Despite high prevalence, detection rate of subclinical hypothyroidism is very low. Carrying out epidemiological study on national scale is need of the hour, as lack of typical clinical features makes the detection less likely and it has numerous complications, if untreated
ABSTRACT
Background: Multiple ligament knee injuries (MLKI) are usually the result of knee dislocations following either high energy motor vehicle accidents or low velocity sport injuries. Hence; we planned the present study to assess and compare two different management protocols for treating patients with multiple knee ligament injuries. Methods: The present study involved comparison of two different methods of management of multiple knee ligament injuries. A total of 20 patients with multiple ligament injured knee were included in the present study. All the patients were broadly divided into two study groups as follows: Group 1: Included patients who were treated with one-stage process .i.e. all ruptured ligaments were repaired or reconstructed at a single stage of operation. Group 2: Included patients who were treated with staged processes .i.e. the entire surgical procedure was carried out in multiple stages Complete follow-up details of all the subjects were obtained. Knee injury and osteoarthritis outcome score during follow-up was used for assessment of results. Results: Mean age of the subjects of group 1 and group 2 was 39.5 years and 36.4 years respectively. While comparing the sports and knee symptoms of the knee injury and osteoarthritis outcome score during follow-up, significant results were obtained. Conclusion: Surgical treatment protocol is reliable mode of treatment for treating multiple ligament injury patients.